Haplotype analysis of APOE intragenic SNPs
نویسندگان
چکیده
منابع مشابه
Finding haplotype tagging SNPs by use of principal components analysis.
The immense volume and rapid growth of human genomic data, especially single nucleotide polymorphisms (SNPs), present special challenges for both biomedical researchers and automatic algorithms. One such challenge is to select an optimal subset of SNPs, commonly referred as "haplotype tagging SNPs" (htSNPs), to capture most of the haplotype diversity of each haplotype block or gene-specific reg...
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UNLABELLED Haplotypes defined by common single nucleotide polymorphisms (SNPs) have important implications for mapping of disease genes and human traits. Often only a small subset of the SNPs is sufficient to capture the full haplotype information. Such subsets of markers are called haplotype tagging SNPs (htSNPs). Although htSNPs can be identified by eye, efficient computer algorithms and flex...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2018
ISSN: 1471-2202
DOI: 10.1186/s12868-018-0413-4